The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. On day three I had a headache and felt heavy/exhausted, which lasted a few days. If you think there has been an overdose, call your poison control center or get medical care right away. With slow IV injection, the drug is given as a single, slow injection into your vein. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Seriousside effectsshould be reported to a physician and/orPharmDfor medical advice. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. Theseside effectsmay last as long as they are undercancer treatment. Limited data indicate that breastmilk iron is not increased after intravenous infusion of Venofer. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. Pain, swelling, or redness at the injection site may occur. The researchers looked to see how well each drug worked to increase peoples hemoglobin level. (A generic drug is an exact copy of the active drug in a brand-name medication.) Blood tests may be needed to check for unwanted effects. Since someallergic reactionscan belife-threatening, its essential to discuss any adverse events previously experienced with the prescribingphysician. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. An iron infusion is a way to increase the body's iron levels quickly. endobj If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. Do not exceed 1,500 mg of iron per dosing course. Mild side effects of Injectafer can include:*. If youre taking iron pills, be sure to tell your doctor before starting Injectafer. Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. If you have more questions about how Injectafer will affect your anemia, talk with your doctor. Discuss the risks and benefits with your doctor. If youre interested in finding an alternative to Injectafer, talk with your doctor. In one study, treatment with Injectafer was compared with that of iron thats taken by mouth. Cancer patients who have anemia and are taking an ESA. Your doctor will recommend whether you should stop taking your multivitamin or any other supplements. The actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis. These lists contain examples of serious side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). muscle pain. Venofer Side Effects. People who weigh 110 pounds (about 50 kilograms) or more will receive two separate Injectafer doses of 750 milligrams each. Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. And this can lead to anemia, including IDA. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. Injectafer is approved to treat iron deficiency anemia (IDA). MNT is the registered trade mark of Healthline Media. After getting each dose of Injectafer, your healthcare professional will monitor you for at least 30 minutes. If you do breastfeed while youre taking Injectafer, the drugs manufacturer recommends that you monitor your child for side effects of the drug. Properly discard this product when it is expired or no longer needed. Venofer also comes as a liquid thats given by either IV infusion or a slow IV injection. Once inside your body, ferric carboxymaltose releases iron into your system. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Typical Injectafer doses for iron deficiency anemia (IDA) depends on your body weight. This information is not specific medical advice and does not replace information you receive from the healthcare provider. In severe cases, it can cause asthma-like symptoms, such as wheezing and difficulty breathing. other treatments you receive, you will need to go back for several treatments with Venofer. In the first group, some people continued taking iron by mouth, while other people took Injectafer. Both Injectafer and Venofer belong to a class of medications called iron replacement products. Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. Excessive amounts of Venofer may lead to a condition called iron overload, which may be harmful. However, not treating iron deficiency anemia during pregnancy may cause complications such as premature birth or low birth weight. Injectafer isnt known to interact with any other medications, herbs, supplements, or foods. There may be risks to the mother and fetus associated with untreated IDA in pregnancy. Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. Learn more about the types of tests and treatment. IQVIA [NSP Audit from MAT November 2013 to November 2018]. With IV infusion, the drug is given as a slow drip into your vein over a period of time. Although a single administration of FCM frequently causes transient hypophosphatemia, a 2016 study showed that repeated treatment with FCM is associated with a high risk of developing severe and prolonged hypophosphatemia and should therefore be monitored. But if they become more severe or dont go away, talk with your doctor or pharmacist. Be ready to tell or show what was taken, how much, and when it happened. Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. Do not exceed 1,500 mg of iron per dosing course. He said sometimes the reaction does show up after a few doses and unfortunately it takes longer to get over it. These changes could help improve your anemia on a long-term basis. People with IDA have low blood levels of hemoglobin. Before taking Injectafer, talk with your doctor about your health history. For more information about taking Injectafer during pregnancy, see the section Injectafer and pregnancy above. Always review your medical history with the treatingphysician. This is not a complete list of side effects and others may occur. WebMD does not provide medical advice, diagnosis or treatment. And this can affect how well those parts of your body are able to work. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. In clinical studies, people who took Injectafer still had iron in their system that was released by the drug 24 days after theyd gotten their injection. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. (For more information on Venofer, see the Injectafer vs. Venofer section above). There isnt a known interaction between Injectafer and alcohol. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Venofer. As described just above in the Allergic reaction section, some people may have an allergic reaction after getting a dose of Injectafer. Injectafer can be exposed to temperatures between 59F to 86F (15C to 30F) for a short period of time. 3 0 obj Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. Constipation,dry mouth, headaches, upset stomach, and many othercommonside effectscan greatly affect peoples quality of life, though. Fortunately, knowing how longside effectslast can help those suffering know what to donext. No, Injectafer itself wont make you gain weight. Injectafer and Venofer are both brand-name drugs. xmq92\Kz!yIP}2~(?c/JUCK2~o_N=>K$o/_7'Z+nRkKM^y{u|ZFh$v}]O~vfo=.GowGFodVj-[-~x]Kg~9H'%h={OX/#S|Mc~|]_2nv`wwotn/+$G[{hGrP}sbZG-RGf#l~~l|Qnccml_iPy]G\17c,yPF[28z&I'+B(?rrvi,G?}/;'?;pm>?.i42ONmk~ai_u0z9o_? Low iron saturation, or iron deficiency, has various possible causes. You may report side effects to the FDA at 1-800-332-1088. Health careproviderscan provide information on how longside effectslast by checking amedication guide. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. No, you most likely wont take Injectafer long term. It belongs to a class of medications called iron replacement products. Tell your doctor if you are pregnant or plan to become pregnant. Then the study was split into the following two groups, which are discussed below. An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. (A medication class is a group of medications that work in a similar way.). Injectafer contains the active drug ferric carboxymaltose, while Feraheme contains the active drug ferumoxytol. During pregnancy, this medication should be used only when clearly needed. The Injectafer dosage your doctor prescribes will depend on your body weight. Injectafer is a brand-name prescription drug. Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Youll receive doses of Injectafer from a healthcare professional at a medical facility. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. ByDr. If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. We cancelled my 5th because of the reaction. They can tell you about other medications that may work well for you. Talk with the doctor. Iron infusions are given directly into a vein. I used to get a different type but my . So theres no recommended pediatric dosage for Injectafer. An LSD comedown is when the mental and hallucinatory effects have worn . However, consuming large amounts of alcohol can actually cause anemia in some people. Dilute Venofer in a maximum of 250 mL of 0.9% NaCl. Side effects from HRT depend on a number of factors: FG Trade/E+ sia Getty Images Side effects like nausea and low blood pressure are common with most iron infusions. Daiichi Sankyo, Inc., the manufacturer of Injectafer, offers a program called injectconnect, which may help lower the cost of the drug. Following an LSD trip, users may experience a sort of 'comedown.'. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. Version: 7.01. Some products that may interact with this drug include: vitamin products, other iron-containing products. Before you receive Venofer, tell your doctor if you have low blood pressure, hepatitis, or if you have received many blood transfusions in the past. All of the people took iron by mouth for 2 weeks. There have also been reports of serious allergic reactions to Venofer. Its given by either intravenous (IV) infusion or slow IV injection. Theyll recommend how to manage your condition. Injectafer helps to treat IDA by providing an iron infusion directly into your body. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Upset stomach or throwing up. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. If you are breastfeeding, tell your doctor if you notice diarrhea or constipation in the nursing baby. For people weighing 50 kg (about 110 lb) or more, administer Injectafer in two doses of 750 mg, at least 7 days apart. This way, if you have an allergic reaction to Injectafer, your healthcare professional can treat your reaction. Read all information given to you. On the other hand, some people may have a poor appetite that goes away when their anemia is treated. The oral form of the drug, called sucroferric oxyhydroxide and used . After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. Serious side effects from Injectafer arent common, but they can occur. These are not all of the side effects that may occur. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. In clinical trials,. Together, you and your doctor can develop a treatment plan thats best for you. Consult your doctor before breast-feeding. <> This document does not contain all possible drug interactions. Remember that it is best to get your vitamins and minerals from food whenever possible. Can diet help improve depression symptoms? With IV infusion, the drug is given as a slow drip into your vein over a period of time. The time it takes to infuse Venofer (iron sucrose) depends on your age, if you're on dialysis, and the type of dialysis you need. One class of immune checkpoint inhibitors targets the protein PD-1, which acts as a brake to keep the immune system in check. These lists contain examples of serious side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). Undergoingcancer treatmentwithradiation therapyorchemotherapy drugsmay result inhair loss, which can be devastating to somepeople. You will be watched closely by your doctor for 30 minutes after each dose. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. Some may be a better fit for you than others. For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. Also tell them about any vitamins, herbs, and supplements you use. If you have symptoms of a low phosphorus level, call your doctor. Vomiting. In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. This can be very helpful in . And Feraheme is approved for use in adults who have CKD who may or may not need dialysis. Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; However, some people can experienceside effectsfor much longer - days, months, or indefinitely. weakness. Do not share your drugs with others and do not take anyone else's drugs. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. This website is intended for use by US healthcare professionals only. But some people have a delayed allergic reaction to certain drugs. For additional information, contact your healthcare provider. And this type of reaction is possible even if you didnt have a reaction to your first dose of the drug. Venofer pregnancy and breastfeeding warnings. Dr. Colby holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford Universitys Graduate School of Business, and a degree in Genetics with Honors from the University of Michigan. The potential side effects of Daxxify are nearly identical to that of Botox bruising, headaches, and droopy eyelids with one big difference: They could last longer. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. It is very important that your doctor check you closely while you are receiving this medicine. Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. 1 0 obj Weight changes may be due to symptoms of anemia improving. To help make sure that you dont miss an appointment for your Injectafer dose, try setting an appointment reminder on your phone. The drug helps increase your hemoglobin level back to a value thats within the normal range. This is why they have a programcalledMedWatchthat encourages Americans to report adversereactions. Its responsible for carrying oxygen throughout your body. Erectile dysfunction, anothercommonside effect, can affect life significantly leading to depression and failedrelationships. Hemoglobin is a protein thats found in your RBCs. After receiving IV iron therapy, you will be monitored for 30 minutes to make sure you do not have an allergic reaction or a drop in blood pressure. This survey is being conducted by the WebMD marketing sciences department. Iron infusion side effects vary depending on which form is being used. A healthcare provider will give you this injection. Keep in mind that the risk of certain pregnancy-related problems can be increased if iron deficiency anemia (IDA) is left untreated. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. This gives a total cumulative dose of 1,500 mg of Injectafer. Injectafer contains the active drug ferric carboxymaltose. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Venofer only for the indication prescribed. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. Venofer treatment may be repeated if iron deficiency reoccurs. If you have a severe allergic reaction to Injectafer after youve left the medical facility where you received your dose of the drug, call your doctor right away. Procedure Details Sharing this information can help you avoid potential interactions. Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away. Heres some detail on certain side effects this drug may cause. Effectiveness of Injectafer compared with iron thats taken by mouth. What Is the Cost of Whole Genome Sequencing (WGS)? (Hemoglobin is a protein thats found in your red blood cells.). Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. }|54U|O~?|_v;f\o^(W+/-|^)O65_)rd sm }[x[)y.z Wz?9_jV0ub,`g`s?oXOSp/Kgw$b!Vb$;IvBVR9n|\0ln=;/=,mgw@do,[";/8nJL{n}Bb-|^6[~>a_1H'^M:^vv=iM+x|+Y Throw away unused or expired drugs. You may report side effects to the FDA at 1-800-332-1088. * Feraheme has a boxed warning for this side effect. Call your doctor for instructions if you miss an appointment for your Venofer injection. If you have iron deficiency anemia (IDA), consuming moderate amounts of alcohol may be safe, if your doctor tells you its OK. (With IDA, you have a low level of red blood cells thats caused by not having enough iron.). Last updated on Feb 20, 2023. Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. The benefit of treating your condition during pregnancy may outweigh any risks. You should not be treated with this medicine if you have ever had an allergic reaction to an iron injection. The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. Which tests can diagnose iron deficiency anemia? In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. Selected from data included with permission and copyrighted by First Databank, Inc. Medically reviewed by Sanjai Sinha, MD. The drug helps increase your hemoglobin level back to a value thats within the normal range. The dosing for iron replacement treatment in pediatric patients less than 2 years old with Peritoneal or Hemodialysis-Dependent CKD or Non-Dialysis-Dependent CKD have not been established. You are encouraged to report side effects to American Regent, Inc. at 1-800-734-9236 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. It depends. This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. If youre not sure if youll need to get prior authorization for Injectafer, contact your insurance company. If you have questions about the best diet for you during Injectafer treatment, talk with your doctor. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. Many people using this medication do not have serious side effects. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. I can't take oral supplements because they cause horrible debilitating Constipation. These people may lose weight as their anemia improves because theyre more active. Some people are simply allergic to an active ingredient in the medication, so the body responds undesirably. Very bad and sometimes deadly allergic side effects have rarely happened. . Nose or throat irritation. If a person does not have an allergic response or any other unanticipated reactions, a doctor will administer the remaining iron. Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. With anemia, you have a low level of red blood cells (RBCs) in your body. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Innovators Monograph Its because everyones body is different. All rights reserved. Depending on your doctors instructions and They can give you tips on how to deal with any side effects that may be bothersome. In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. Call your doctor for medical advice about side effects. These side effects may include constipation and diarrhea. Side effectsare uncomfortable reactions to medications or drugs. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. In some cases, they may even recommend that you use a drug other than Injectafer to treat your anemia. Canada residents can call a provincial poison control center. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. There may be drug take-back programs in your area. But you dont necessarily need to eat these foods unless your doctor tells you to do so. Serious side effects should be reported to a physician and/or PharmD for medical advice. With slow IV injection, the drug is given as a single, slow injection into your vein. Venofer may cause significant hypotension (decreased blood pressure). You may report side effects to FDA at 1-800-FDA-1088. If needed, theyll recommend treatment, including certain medications. Injectafer isnt a medication that youll take regularly on a schedule. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. This medication is given by injection into a vein as directed by your doctor. Potential injection site discoloration has happened. Check with your pharmacist if you have questions about the best way to throw out drugs. But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. For more information about Injectafers approved uses, see the section Injectafer uses below. This medicine may cause serious types . Hes an expert in genetic testing, genetic analysis, andprecision medicine. Injectafer contains the active drug ferric carboxymaltose. Does Venofer Vial interact with other medications? These are not all the side effects that may occur; contact your healthcare provider if you have questions. And these two doses need to be separated by at least 7 days. However, some people may have weight changes as they have improvement in their anemia, which Injectafer is used to treat. Cholesterolmedication may reduce the risk of a stroke but it can decrease the quality of life for some people but causingweight gain, dizziness, nausea, and musclepain. Copyright 1996-2023 Cerner Multum, Inc. Talk with your doctor. Pain, swelling, or redness at the injection site may occur. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. Drug interactions: DayQuil can interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. Iron-refractory iron deficiency anemia (IRIDA) is a genetic form of anemia. (A generic drug is an exact copy of the active drug in a brand-name medication.). (And Injectafer is used to treat IDA.) Its responsible for carrying oxygen throughout your body. Your body then uses the iron from Injectafer to make hemoglobin and new RBCs. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Its FDA-approved to treat iron deficiency anemia (IDA) in adults. However, to be safe, tell your doctor or pharmacist about all prescription, over-the-counter, and other drugs you take before taking Injectafer.